A total of 50 patients were
included in the mirror-design naturalistic study. The types of service
utilization, medication costs, and overall costs were measured in a
1-year period prior to and then after quetiapine initiation. Clinical
measures to document symptom improvement were done at medication
initiation and 6 months later.


  • 72% reduction in inpatient utilization occurred after medication was initiated.
  • 60% reduction in acute ER utilization
  • 170% increase in outpatient services correlating with greater patient stabilization
  • Overall mean costs savings of $12 per pt/month. (n=50)
  • Significant  improvement in symptoms of schizophrenia PANSS score decreased by 20%-60%

Service Utilization Changes&nbsp

Intent to Treat: Cost Changes

Mean Cost Change Over 2 Years