Olanzapine (Zyprexa): Clinical and Economic Outcomes
A total of 56 patients were included in this two-year study. Fifty-six patients continued to receive olanzapine for 12 consecutive months. The types of service utilization, medication costs, and overall costs were measured in a 1-year period prior to and then after olanzapine initiation. Clinical measures to document symptom improvement were done at medication initiation and 6 months later.
Results
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85% reduction in inpatient utilization occurred after medication was initiated.
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80% reduction in acute ER utilization
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23% increase in outpatient services correlating with greater patient stabilization
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Overall mean costs savings of $296 per pt/month. (n=56)
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Significant improvement in symptoms of schizophrenia
Service
Utilization Changes 
Intent to Treat: Cost Changes
Mean Cost Changes Over 2 Years
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